E-AB-63782
NAE1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63782
- Additional Names:
- A-116A10.1,APPBP1,HPP1,NAE1,ula-1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human NAE1 (NP_003896.1).
- Uniprot:
- Q13564
- Synonyms:
- A-116A10.1;amyloid beta precursor protein binding protein 1, 59kDa;amyloid beta precursor protein-binding protein 1, 59 kDa;amyloid beta precursor protein-binding protein 1, 59kD;amyloid protein-binding protein 1;APP-BP1;APPBP1;HPP1;NEDD8-activating enzyme E1 regulatory subunit;NEDD8-activating enzyme E1 subunit;proto-oncogene protein 1;protooncogene protein 1;ula-1
- Extra Details:
- The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice