E-AB-63725
MAPRE1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63725
- Additional Names:
- EB1,MAPRE1
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MAPRE1 (NP_036457.1).
- Uniprot:
- Q15691
- Synonyms:
- adenomatous polyposis coli-binding protein EB1;APC-binding protein EB1;EB1;end-binding protein 1;microtubule-associated protein RP/EB family member 1
- Extra Details:
- The protein encoded by this gene was first identified by its binding to the APC protein which is often mutated in familial and sporadic forms of colorectal cancer. This protein localizes to microtubules, especially the growing ends, in interphase cells. During mitosis, the protein is associated with the centrosomes and spindle microtubules. The protein also associates with components of the dynactin complex and the intermediate chain of cytoplasmic dynein. Because of these associations, it is thought that this protein is involved in the regulation of microtubule structures and chromosome stability. This gene is a member of the RP/EB family.
- Shipping Conditions:
- Blue Ice