SART3 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-63630
Additional Names:: DSAP1,P100,RP11-13G14,SART3,TIP110,p110,p110(nrb)
Application:: WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SART3 (NP_055521.1).
Uniprot:: Q15020
Synonyms:: DSAP1;HIV-1 Tat-interacting protein of 110kDa;hSART-3;P100;p110;p110 nuclear RNA-binding protein;p110(nrb);PRP24 homolog;RP11-13G14;SART-3;squamous cell carcinoma antigen recognized by T cells 3;squamous cell carcinoma antigen recognized by T-cells 3;tat-interacting protein of 110 kDa;TIP110
Extra Details:: The protein encoded by this gene is an RNA-binding nuclear protein that is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is found to be an important cellular factor for HIV-1 gene expression and viral replication. It also associates transiently with U6 and U4/U6 snRNPs during the recycling phase of the spliceosome cycle. This encoded protein is thought to be involved in the regulation of mRNA splicing.