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E-AB-63610

NPTX2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-63610
Additional Names:
NARP,NP-II,NP2,NPTX2
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human NPTX2 (NP_002514.1).
Uniprot:
P47972
Synonyms:
apexin;NARP;neuronal activity-regulated pentaxin;neuronal pentraxin II;neuronal pentraxin-2;NP-II;NP2
Extra Details:
This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Shipping Conditions:
Blue Ice