E-AB-63587
DDX3Y Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63587
- Additional Names:
- DBY,DDX3Y
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human DDX3Y (NP_001116137.1).
- Uniprot:
- O15523
- Synonyms:
- ATP-dependent RNA helicase DDX3Y;DBY;DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked;DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked;DEAD box protein 3, Y-chromosomal;DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide, Y chromosome
- Extra Details:
- The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, and in the formation of intramolecular interactions. This protein shares high similarity to DDX3X, on the X chromosome, but a deletion of this gene is not complemented by DDX3X. Mutations in this gene result in male infertility, a reduction in germ cell numbers, and can result in Sertoli-cell only sydrome. Pseudogenes sharing similarity to both this gene and the DDX3X paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice