TRIM24 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-63433
Additional Names:: PTC6,RNF82,TF1A,TIF1,TIF1A,TIF1ALPHA,TRIM24,hTIF1
Application:: WB
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TRIM24 (NP_056989.2).
Uniprot:: O15164
Synonyms:: E3 ubiquitin-protein ligase TRIM24;hTIF1;PTC6;RING finger protein 82;RING-type E3 ubiquitin transferase TIF1-alpha;RNF82;TF1A;TIF1;TIF1-alpha;TIF1A;TIF1ALPHA;transcription intermediary factor 1-alpha;transcriptional intermediary factor 1;Tripartite motif-containing protein 24
Extra Details:: The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.