E-AB-63213
SESN3 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63213
- Additional Names:
- SESN3,SEST3,sestrin-3
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human SESN3 (NP_653266.2).
- Uniprot:
- P58005
- Synonyms:
- SEST3;sestrin-3
- Extra Details:
- This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice