E-AB-63167
CLEC7A Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63167
- Additional Names:
- BGR,CANDF4,CD369,CLEC7A,CLECSF12,DECTIN1,SCARE2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human CLEC7A (NP_922938.1).
- Uniprot:
- Q9BXN2
- Synonyms:
- beta-glucan receptor;BGR;C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12;C-type lectin domain family 7 member A;C-type lectin superfamily member 12;CANDF4;CD369;CLECSF12;DC-associated C-type lectin 1;dectin-1;DECTIN1;Dendritic cell-associated C-type lectin 1;dendritic cell-associated C-type lectin-1;lectin-like receptor 1;SCARE2
- Extra Details:
- This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
- Shipping Conditions:
- Blue Ice