E-AB-63155
EPS15L1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63155
- Additional Names:
- EPS15L1,EPS15R
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human EPS15L1 (NP_001245304.1).
- Uniprot:
- Q9UBC2
- Synonyms:
- epidermal growth factor receptor substrate 15-like 1;epidermal growth factor receptor substrate EPS15R;eps15-related protein;EPS15R
- Extra Details:
- Epidermal growth factor receptor substrate 15-like 1is aproteinthat in humans is encoded by theEPS15L1gene. Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR), internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2. Interacts with EPS15, AGFG1/HRB and AGFG2/HRBL. Associates with the clathrin-associated adapter protein complex 2 (AP-2) By similarity. Interacts with FCHO1. Interacts with FCHO2. Interacts (via EH domains) with DAB2.
- Shipping Conditions:
- Blue Ice