E-AB-63089
APPL1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-63089
- Additional Names:
- APPL,APPL1,DIP13alpha,MODY14
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human APPL1 (NP_036228.1).
- Uniprot:
- Q9UKG1
- Synonyms:
- adapter protein containing PH domain, PTB domain and leucine zipper motif 1;adaptor protein containing pH domain, PTB domain and leucine zipper motif 1;adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1;AKT2 interactor;APPL;DCC-interacting protein 13-alpha;dip13-alpha;DIP13alpha;MODY14;signaling adaptor protein DIP13alpha
- Extra Details:
- The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
- Shipping Conditions:
- Blue Ice