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E-AB-62785

HMGCL Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-62785
Additional Names:
HL,HMGCL
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human HMGCL (NP_000182.2).
Uniprot:
P35914
Synonyms:
3-hydroxy-3-methylglutarate-CoA lyase;3-hydroxymethyl-3-methylglutaryl-CoA lyase;3-hydroxymethyl-3-methylglutaryl-Coenzyme A lyase;HL;HMG-CoA lyase;hydroxymethylglutaricaciduria;hydroxymethylglutaryl-CoA lyase, mitochondrial;mitochondrial 3-hydroxy-3-methylglutaryl-CoA lyase
Extra Details:
The protein encoded by this gene belongs to the HMG-CoA lyase family. It is a mitochondrial enzyme that catalyzes the final step of leucine degradation and plays a key role in ketone body formation. Mutations in this gene are associated with HMG-CoA lyase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice