E-AB-62733
ETFA Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-62733
- Additional Names:
- EMA,ETFA,GA2,MADD
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human ETFA (NP_000117.1).
- Uniprot:
- P13804
- Synonyms:
- alpha-ETF;electron transfer flavoprotein alpha subunit;electron transfer flavoprotein subunit alpha, mitochondrial;electron transfer flavoprotein, alpha polypeptide;EMA;epididymis secretory sperm binding protein;GA2;glutaric aciduria II;MADD
- Extra Details:
- ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene.
- Shipping Conditions:
- Blue Ice