E-AB-62714
DGUOK Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-62714
- Additional Names:
- DGUOK,MTDPS3,NCPH,PEOB4,dGK
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human DGUOK
- Uniprot:
- Q16854
- Synonyms:
- deoxyadenosine kinase, mitochondrial;deoxyguanosine kinase, mitochondrial;dGK;MTDPS3;NCPH;NCPH1;PEOB4
- Extra Details:
- In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
- Shipping Conditions:
- Blue Ice