E-AB-62499
MIB1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-62499
- Additional Names:
- DIP-1,DIP1,LVNC7,MIB,MIB1,ZZANK2,ZZZ6
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MIB1 (NP_065825.1).
- Uniprot:
- Q86YT6
- Synonyms:
- DAPK-interacting protein 1;DIP-1;DIP1;E3 ubiquitin-protein ligase MIB1;LVNC7;MIB;Mind bomb homolog 1;mindbomb E3 ubiquitin protein ligase 1;RING-type E3 ubiquitin transferase MIB1;ubiquitin ligase mind bomb;zinc finger ZZ type with ankyrin repeat domain protein 2;ZZANK2;ZZZ6
- Extra Details:
- This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1).
- Shipping Conditions:
- Blue Ice