E-AB-62474
LEPREL1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-62474
- Additional Names:
- LEPREL1,MCVD,MLAT4,P3H2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human LEPREL1 (NP_060662.2).
- Uniprot:
- Q8IVL5
- Synonyms:
- leprecan-like 1;Leprecan-like protein 1;LEPREL1;MCVD;MLAT4;myxoid liposarcoma-associated protein 4;procollagen-proline 3-dioxygenase 2;prolyl 3-hydroxylase 2;prolyl 3-hydroxylase 3
- Extra Details:
- This gene encodes a member of the prolyl 3-hydroxylase subfamily of 2-oxo-glutarate-dependent dioxygenases. These enzymes play a critical role in collagen chain assembly, stability and cross-linking by catalyzing post-translational 3-hydroxylation of proline residues. Mutations in this gene are associated with nonsyndromic severe myopia with cataract and vitreoretinal degeneration, and downregulation of this gene may play a role in breast cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Shipping Conditions:
- Blue Ice