PRPF8 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-62352
Additional Names:: HPRP8,PRP8,PRPC8,PRPF8,PRPF8 ,RP13,SNRNP220
Application:: IHC, WB, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: A synthetic peptide of human PRPF8 (NP_006436.3).
Uniprot:: Q6P2Q9
Synonyms:: 220 kDa U5 snRNP-specific protein;apoptosis-regulated protein 1;apoptosis-regulated protein 2;HPRP8;p220;pre-mRNA-processing-splicing factor 8;precursor mRNA processing protein;PRP8;PRP8 homolog;PRP8 pre-mRNA processing factor 8 homolog;PRPC8;RP13;SNRNP220;splicing factor Prp8;U5 snRNP-specific protein (220 kD), ortholog of S. cerevisiae Prp8p
Extra Details:: Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.