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E-AB-62344

YAP1 Polyclonal Antibody

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£211.50

Was £235.00

SKU:
E-AB-62344
Additional Names:
COB1,YAP,YAP1,YAP2,YAP65,YKI
Application:
IHC, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human YAP1 (NP_001123617.1).
Uniprot:
P46937
Synonyms:
65 kDa Yes-associated protein;COB1;protein yorkie homolog;transcriptional coactivator YAP1;YAP;YAP2;YAP65;Yes associated protein 1;yes-associated protein 2;yes-associated protein YAP65 homolog;YKI;yorkie homolog
Extra Details:
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Shipping Conditions:
Blue Ice