E-AB-62317
EIF5B Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-62317
- Additional Names:
- EIF5B,IF2
- Application:
- IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human EIF5B (NP_056988.3).
- Uniprot:
- O60841
- Synonyms:
- eIF-5B;eukaryotic translation initiation factor 5B;IF2;translation initiation factor IF-2;translation initiation factor IF2
- Extra Details:
- Accurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B. This gene encodes eIF5B. Factors eIF1A and eIF5B interact on the ribosome along with other initiation factors and GTP to position the initiation methionine tRNA on the start codon of the mRNA so that translation initiates accurately.
- Shipping Conditions:
- Blue Ice