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E-AB-62305

TRIP12 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-62305
Additional Names:
TRIP-12,TRIP12,ULF
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TRIP12 (NP_001271143.1).
Uniprot:
Q14669
Synonyms:
E3 ubiquitin-protein ligase for Arf;E3 ubiquitin-protein ligase TRIP12;HECT-type E3 ubiquitin transferase TRIP12;MRD49;probable E3 ubiquitin-protein ligase TRIP12;thyroid receptor interacting protein 12;Thyroid receptor-interacting protein 12;TR-interacting protein 12;TRIP-12;TRIPC;ULF
Extra Details:
The protein encoded by this gene is an E3 ubiquitin-protein ligase involved in the degradation of the p19ARF/ARF isoform of CDKN2A, a tumor suppressor. The encoded protein also plays a role in the DNA damage response by regulating the stability of USP7, which regulates tumor suppressor p53.
Shipping Conditions:
Blue Ice