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E-AB-62303

SOCS6 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-62303
Additional Names:
CIS-4,CIS4,HSPC060,SOCS-4,SOCS-6,SOCS4,SOCS6,SSI4,STAI4,STATI4
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human SOCS6 (NP_004223.2).
Uniprot:
O14544
Synonyms:
CIS-4;CIS4;cytokine-inducible SH2 protein 4;HSPC060;SOCS-4;SOCS-6;SOCS4;SSI4;STAI4;STAT induced STAT inhibitor-4;STATI4;suppressor of cytokine signaling 4;suppressor of cytokine signaling 6
Extra Details:
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.
Shipping Conditions:
Blue Ice