E-AB-62262
WHSC1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-62262
- Additional Names:
- KMT3F,KMT3G,MMSET,NSD2,REIIBP,TRX5,WHS,WHSC1
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human WHSC1 (NP_579877.1).
- Uniprot:
- O96028
- Synonyms:
- histone-lysine N-methyltransferase NSD2;IL5 promoter REII region-binding protein;KMT3F;KMT3G;MMSET;multiple myeloma SET domain containing protein type III;Multiple myeloma SET domain-containing protein;nuclear SET domain-containing protein 2;probable histone-lysine N-methyltransferase NSD2;Protein trithorax-5;REIIBP;trithorax/ash1-related protein 5;TRX5;WHS;WHSC1;Wolf-Hirschhorn syndrome candidate 1;Wolf-Hirschhorn syndrome candidate 1 protein
- Extra Details:
- This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
- Shipping Conditions:
- Blue Ice