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E-AB-62232

TADA2A Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-62232
Additional Names:
ADA2,ADA2A,KL04P,TADA2A,TADA2L,hADA2
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human TADA2A (NP_001159577.2).
Uniprot:
O75478
Synonyms:
ADA2;ADA2-like protein;ADA2A;hADA2;KL04P;TADA2L;transcriptional adapter 2-alpha;Transcriptional adapter 2-like;transcriptional adaptor 2 alpha
Extra Details:
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.
Shipping Conditions:
Blue Ice