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E-AB-62045

ERCC8 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-62045
Additional Names:
CKN1,CSA,ERCC8,UVSS2
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human ERCC8 (NP_000073.1).
Uniprot:
Q13216
Synonyms:
CKN1;cockayne syndrome WD repeat protein CSA;Cockayne syndrome WD-repeat protein CSA;CSA;DNA excision repair protein ERCC-8;excision repair cross-complementation group 8;excision repair cross-complementing rodent repair deficiency, complementation group 8;UVSS2
Extra Details:
This gene encodes a WD repeat protein, which interacts with Cockayne syndrome type B (CSB) protein and with p44 protein, a subunit of the RNA polymerase II transcription factor IIH. Mutations in this gene have been identified in patients with hereditary disease Cockayne syndrome (CS). CS cells are abnormally sensitive to ultraviolet radiation and are defective in the repair of transcriptionally active genes. Several transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice