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E-AB-62031

TNFRSF8 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-62031
Additional Names:
CD30,D1S166E,Ki-1,TNFRSF8
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human TNFRSF8
Uniprot:
P28908
Synonyms:
CD30;CD30L receptor;cytokine receptor CD30;D1S166E;Ki-1;Ki-1 antigen;lymphocyte activation antigen CD30;tumor necrosis factor receptor superfamily member 8
Extra Details:
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Shipping Conditions:
Blue Ice