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E-AB-62004

AHR Polyclonal Antibody

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£211.50

Was £235.00

SKU:
E-AB-62004
Additional Names:
AHR,bHLHe76
Application:
IHC
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human AHR (NP_001612.1).
Uniprot:
P35869
Synonyms:
ah receptor;AH-receptor;aromatic hydrocarbon receptor;aryl hydrocarbon receptor;bHLHe76;class E basic helix-loop-helix protein 76;RP85
Extra Details:
The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm, upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.
Shipping Conditions:
Blue Ice