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E-AB-61902

RHOH Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-61902
Additional Names:
ARHH,RHOH,TTF
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human RHOH (NP_004301.1).
Uniprot:
Q15669
Synonyms:
ARHH;GTP-binding protein TTF;ras homolog gene family, member H;rho-related GTP-binding protein RhoH;Translocation three four protein;TTF;TTF, translocation three four
Extra Details:
The protein encoded by this gene is a member of the Ras superfamily of guanosine triphosphate (GTP)-metabolizing enzymes. The encoded protein is expressed in hematopoietic cells, where it functions as a negative regulator of cell growth and survival. This gene may be hypermutated or misexpressed in leukemias and lymphomas. Chromosomal translocations in non-Hodgkin's lymphoma occur between this locus and B-cell CLL/lymphoma 6 (BCL6) on chromosome 3, leading to the production of fusion transcripts. Alternative splicing in the 5' untranslated region results in multiple transcript variants that encode the same protein.
Shipping Conditions:
Blue Ice