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E-AB-61822

TRPM2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-61822
Additional Names:
EREG1,KNP3,LTRPC2,LTrpC-2,NUDT9H,NUDT9L1,TRPC7,TRPM2
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
A synthetic peptide of human TRPM2 (NP_003298.1).
Uniprot:
O94759
Synonyms:
EREG1;estrogen-responsive element-associated gene 1 protein;KNP3;long transient receptor potential channel 2;LTrpC-2;LTRPC2;NUDT9H;NUDT9L1;transient receptor potential cation channel subfamily M member 2;transient receptor potential channel 7;transient receptor potential melastatin 2;TRPC7
Extra Details:
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known.
Shipping Conditions:
Blue Ice