E-AB-61816
SF3B2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-61816
- Additional Names:
- Cus1,SAP145,SF3B145,SF3B2,SF3b1,SF3b150
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human SF3B2 (NP_006833.2).
- Uniprot:
- Q13435
- Synonyms:
- Cus1;pre-mRNA splicing factor SF3b 145 kDa subunit;Pre-mRNA-splicing factor SF3b 145 kDa subunit;SAP 145;SAP145;SF3b1;SF3B145;SF3b150;spliceosome associated protein 145;Spliceosome-associated protein 145;splicing factor 3B subunit 2;splicing factor 3b, subunit 2, 145kD;splicing factor 3b, subunit 2, 145kDa
- Extra Details:
- This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
- Shipping Conditions:
- Blue Ice