E-AB-61800
PSMB10 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-61800
- Additional Names:
- LMP10,MECL1,PSMB10,beta2i
- Application:
- IHC, WB, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PSMB10 (NP_002792.1).
- Uniprot:
- P40306
- Synonyms:
- beta2i;LMP10;low molecular mass protein 10;macropain subunit MECl-1;MECL1;multicatalytic endopeptidase complex subunit MECl-1;PRAAS5;proteasome (prosome, macropain) subunit, beta type, 10;proteasome catalytic subunit 2i;proteasome MECl-1;proteasome subunit beta 10;proteasome subunit beta 7i;proteasome subunit beta type-10;proteasome subunit beta-2i;proteasome subunit beta2i;proteasome subunit MECL1
- Extra Details:
- The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.
- Shipping Conditions:
- Blue Ice