PPAN Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-61678
Additional Names:: BXDC3,PPAN,SSF,SSF-1,SSF1,SSF2
Application:: IHC, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human PPAN (NP_064615.3).
Uniprot:: Q9NQ55
Synonyms:: brix domain-containing protein 3;BXDC3;homolog of S. cerevisiae SSF1;P2RY11;P2Y purinoceptor 11;P2Y11;Peter Pan homolog;PPAN;PPAN-P2RY11 protein;PPAN-P2RY11 readthrough transcript;second-step splicing factor 1;SSF;SSF-1;SSF1;SSF1/P2Y11 protein;SSF2;suppressor of sterile four 1;suppressor of SWI4 1 homolog
Extra Details:: The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 as well as to the gene product of the Drosophila gene peter pan (ppan). SSF1 is known to be involved in the second step of mRNA splicing. Both SSF1 and ppan are essential for cell growth and proliferation. Exogenous expression of this gene was reported to reduce the anchorage-independent growth of some tumor cells. Read-through transcription of this gene with P2RY11/P2Y(11), an adjacent downstream gene that encodes an ATP receptor, has been found. These read-through transcripts are ubiquitously present and up-regulated during granulocyte differentiation.