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E-AB-61627

NFYB Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-61627
Additional Names:
CBF-A,CBF-B,HAP3,NF-YB,NFYB
Application:
WB
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human NFYB
Uniprot:
P25208
Synonyms:
CAAT box DNA-binding protein subunit B;CBF-A;CBF-B;CCAAT-binding transcription factor subunit A;HAP3;NF-YB;nuclear transcription factor Y subunit B;nuclear transcription factor Y subunit beta;nuclear transcription factor Y, beta;Transcription factor NF-Y, B subunit
Extra Details:
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence, protein sequence alignments and experiments with mutants.
Shipping Conditions:
Blue Ice