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E-AB-61603

UIMC1 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-61603
Additional Names:
RAP80,UIMC1,X2HRIP110
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human UIMC1 (NP_057374.3).
Uniprot:
Q96RL1
Synonyms:
BRCA1-A complex subunit RAP80;RAP80;receptor-associated protein 80;retinoid X receptor-interacting protein 110;Ubiquitin interaction motif-containing protein 1;X2HRIP110
Extra Details:
This gene encodes a nuclear protein that interacts with Brca1 (breast cancer 1) in a complex to recognize and repair DNA lesions. This protein binds ubiquitinated lysine 63 of histone H2A and H2AX. This protein may also function as a repressor of transcription. Alternative splicing results in multiple transcript variants.
Shipping Conditions:
Blue Ice