E-AB-61586
PTPRE Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-61586
- Additional Names:
- HPTPE,PTPE,PTPRE,R-PTP-EPSILON
- Application:
- IHC
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PTPRE (NP_006495.1).
- Uniprot:
- P23469
- Synonyms:
- HPTPE;protein tyrosine phosphatase, receptor type, epsilon polypeptide;PTPE;R-PTP-EPSILON;receptor-type tyrosine-protein phosphatase epsilon
- Extra Details:
- The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels.
- Shipping Conditions:
- Blue Ice