E-AB-61511
MTF2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-61511
- Additional Names:
- M96,MTF2,PCL2,TDRD19A,dJ976O13.2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human MTF2
- Uniprot:
- Q9Y483
- Synonyms:
- dJ976O13.2;hPCl2;M96;metal regulatory transcription factor 2;metal-response element DNA-binding protein M96;metal-response element-binding transcription factor 2;PCL2;polycomb-like 2;polycomb-like protein 2;putative DNA binding protein;TDRD19A;tudor domain containing 19A
- Extra Details:
- Polycomb group (PcG protein that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3 and recruits the PRC2 complex, thus enhancing PRC2 H3K27me3 methylation activity. Regulates the transcriptional networks during embryonic stem cell self-renewal and differentiation (By similarity. Promotes recruitment of the PRC2 complex to the inactive X chromosome in differentiating XX ES cells and PRC2 recruitment to target genes in undifferentiated ES cells (By similarity. Required to repress Hox genes by enhancing H3K27me3 methylation of the PRC2 complex (By similarity. In some conditions may act as an inhibitor of PRC2 activity: able to activate the CDKN2A gene and promote cellular senescence by suppressing the catalytic activity of the PRC2 complex locally (By similarity. Binds to the metal-regulating-element (MRE of MT1A gene promoter (By similarity.
- Shipping Conditions:
- Blue Ice