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E-AB-61497

STAM2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-61497
Additional Names:
Hbp,STAM2,STAM2A,STAM2B
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human STAM2 (NP_005834.4).
Uniprot:
O75886
Synonyms:
Hbp;Hrs-binding protein;HSE1 homolog;signal transducing adapter molecule 2;signal transducing adaptor molecule (SH3 domain and ITAM motif) 2;STAM-2;STAM-like protein containing SH3 and ITAM domains 2;STAM2A;STAM2B
Extra Details:
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
Shipping Conditions:
Blue Ice