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E-AB-61404

HABP2 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-61404
Additional Names:
FSAP,HABP,HABP2,HGFAL,NMTC5,PHBP
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human HABP2 (NP_004123.1).
Uniprot:
Q14520
Synonyms:
factor seven-activating protease;factor VII activating protein;factor VII-activating protease;FSAP;HABP;hepatocyte growth factor activator-like protein;HGFAL;hyaluronan-binding protein 2;hyaluronic acid binding protein 2;NMTC5;PHBP;plasma hyaluronan binding protein;Plasma hyaluronan-binding protein
Extra Details:
This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by hepatocytes and proteolytically processed to generate heavy and light chains that form the mature heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This extracellular protease binds hyaluronic acid and may play a role in the coagulation and fibrinolysis systems. Mutations in this gene are associated with nonmedullary thyroid cancer and susceptibility to venous thromboembolism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
Shipping Conditions:
Blue Ice