TSHB Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-61360
Additional Names:: TSH-B,TSH-BETA,TSHB
Application:: IHC, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human TSHB (NP_000540.2).
Uniprot:: P01222
Synonyms:: thyroid stimulating hormone beta;Thyroid-stimulating hormone subunit beta;thyrotropin beta chain;thyrotropin subunit beta;TSH-B;TSH-BETA
Extra Details:: The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. Thyroid stimulating hormone functions in the control of thyroid structure and metabolism. The protein encoded by this gene is the beta subunit of thyroid stimulating hormone. Mutations in this gene are associated with congenital central and secondary hypothyroidism and Hashimoto's thyroiditis. Alternative splicing of this gene results in multiple transcript variants.