E-AB-61334
SECISBP2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-61334
- Additional Names:
- SBP2,SECISBP2
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human SECISBP2 (NP_076982.3).
- Uniprot:
- Q96T21
- Synonyms:
- SBP2;Sec insertion sequence-binding protein 2;selenocysteine insertion sequence-binding protein 2
- Extra Details:
- The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.
- Shipping Conditions:
- Blue Ice