AGPAT2 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-61187
Additional Names:: 1-AGPAT2,AGPAT2,BSCL,BSCL1,LPAAB,LPAAT-beta
Application:: WB, IF
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human AGPAT2 (NP_006403.2).
Uniprot:: O15120
Synonyms:: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta;1-acylglycerol-3-phosphate O-acyltransferase 2;1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta);1-AGP acyltransferase 2;1-AGPAT 2;1-AGPAT2;BSCL;BSCL1;LPAAB;LPAAT-beta;Lysophosphatidic acid acyltransferase beta;lysophosphatidic acid acyltransferase-beta;testicular tissue protein Li 143
Extra Details:: This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.