E-AB-61150
SP100 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-61150
- Additional Names:
- SP100,lysp100b
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human SP100 (NP_001193631.1).
- Uniprot:
- P23497
- Synonyms:
- lysp100b;nuclear autoantigen Sp-100;nuclear dot-associated Sp100 protein;SP100-HMG nuclear autoantigen;speckled 100 kDa
- Extra Details:
- This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene, one of which encodes a high-mobility group protein.
- Shipping Conditions:
- Blue Ice