SMARCB1 Polyclonal Antibody

Size

£195.30

Was £217.00

SKU:: E-AB-61106
Additional Names:: BAF47,CSS3,INI1,MRD15,PPP1R144,RDT,RTPS1,SMARCB1,SNF5,SNF5L1,SWNTS1,Sfh1p,Snr1,hSNFS
Application:: IHC
Concentration:: 1 mg/ml
Purification:: Affinity Purified
Storage Conditions:: -20[o]C Avoid freeze/thaw cycles.
Supplier:: Elabscience
Host:: Rabbit
Reactivities:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant fusion protein of human SMARCB1 (NP_001007469.1).
Uniprot:: Q12824
Synonyms:: BAF47;BRG1-associated factor 47;CSS3;hSNF5;hSNFS;INI1;integrase interactor 1 protein;malignant rhabdoid tumor suppressor;MRD15;PPP1R144;protein phosphatase 1, regulatory subunit 144;RDT;RTPS1;Sfh1p;SNF5;SNF5 homolog;SNF5L1;Snr1;sucrose nonfermenting, yeast, homolog-like 1;SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1;SWI/SNF-related matrix-associated protein;SWNTS1
Extra Details:: The protein encoded by this gene is part of a complex that relieves repressive chromatin structures, allowing the transcriptional machinery to access its targets more effectively. The encoded nuclear protein may also bind to and enhance the DNA joining activity of HIV-1 integrase. This gene has been found to be a tumor suppressor, and mutations in it have been associated with malignant rhabdoid tumors. Alternatively spliced transcript variants have been found for this gene.