E-AB-60897
PDZK1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60897
- Additional Names:
- CAP70,CLAMP,NHERF-3,NHERF3,PDZD1,PDZK1
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human PDZK1 (NP_001188254.1).
- Uniprot:
- Q5T2W1
- Synonyms:
- CAP70;CFTR-associated protein of 70 kDa;CLAMP;Na(+)/H(+) exchange regulatory cofactor NHE-RF3;Na(+)/H(+) exchanger regulatory factor 3;na/Pi cotransporter C-terminal-associated protein 1;naPi-Cap1;NHERF-3;NHERF3;PDZ domain-containing protein 1;PDZ-containing kidney protein 1;PDZD1;sodium-hydrogen exchanger regulatory factor 3
- Extra Details:
- This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Shipping Conditions:
- Blue Ice