E-AB-60895
KLKB1 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60895
- Additional Names:
- KLK3,KLKB1,PKK,PKKD,PPK
- Application:
- IHC, WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human KLKB1 (NP_000883.2).
- Uniprot:
- P03952
- Synonyms:
- Fletcher factor;kallikrein B, plasma (Fletcher factor) 1;kininogenin;KLK3;PKK;PKKD;plasma kallikrein;plasma prekallikrein;PPK
- Extra Details:
- This gene encodes a glycoprotein that participates in the surface-dependent activation of blood coagulation, fibrinolysis, kinin generation and inflammation. The encoded preproprotein present in plasma as a non-covalent complex with high molecular weight kininogen undergoes proteolytic processing mediated by activated coagulation factor XII to generate a disulfide-linked, heterodimeric serine protease comprised of heavy and light chains. Certain mutations in this gene cause prekallikrein deficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Shipping Conditions:
- Blue Ice