E-AB-60893
GLRX Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60893
- Additional Names:
- GLRX,GRX,GRX1
- Application:
- IHC, IF
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of human GLRX (NP_001112362.1).
- Uniprot:
- P35754
- Synonyms:
- glutaredoxin-1;GRX;GRX1;thioltransferase;thioltransferase-1;TTase-1
- Extra Details:
- This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified.
- Shipping Conditions:
- Blue Ice