E-AB-60685
Uhrf2 Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60685
- Additional Names:
- NIRF,RNF107,TDRD23,UHRF2,URF2,Uhrf2
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant fusion protein of mouse Uhrf2 (NP_659122.2).
- Uniprot:
- Q7TMI3
- Synonyms:
- 2310065A22Rik;AI426270;AW214556;D130071B19Rik;E3 ubiquitin-protein ligase UHRF2;N;Nirf;Np95-like ring finger protein;nuclear protein 97;nuclear zinc finger protein Np97;RING-type E3 ubiquitin transferase UHRF2;ubiquitin-like PHD and RING finger domain-containing protein 2;ubiquitin-like-containing PHD and RING finger domains protein 2
- Extra Details:
- This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
- Shipping Conditions:
- Blue Ice