E-AB-60591
FGR Polyclonal Antibody
Size
£195.30
Was £217.00
- SKU:
- E-AB-60591
- Additional Names:
- FGR,SRC2,c-fgr,c-src2,p55-Fgr,p55c-fgr,p58-Fgr,p58c-fgr
- Application:
- WB
- Concentration:
- 1 mg/ml
- Purification:
- Affinity Purified
- Storage Conditions:
- -20[o]C Avoid freeze/thaw cycles.
- Supplier:
- Elabscience
- Host:
- Rabbit
- Reactivities:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- A synthetic peptide of human FGR (NP_005239.1).
- Uniprot:
- P09769
- Synonyms:
- c-fgr;c-fgr protooncogene;c-src-2 proto-oncogene;c-src2;feline Gardner-Rasheed sarcoma viral oncogene homolog;Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog;p55-c-fgr protein;p55-Fgr;p55c-fgr;p58-Fgr;p58c-fgr;proto-oncogene c-Fgr;proto-oncogene tyrosine-protein kinase FGR;SRC2;tyrosine-protein kinase Fgr;v-fgr feline Gardner-Rasheed sarcoma viral oncogene homolog
- Extra Details:
- This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- Shipping Conditions:
- Blue Ice