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E-AB-60584

CDKN3 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-60584
Additional Names:
CDI1,CDKN3,CIP2,KAP,KAP1
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human CDKN3 (NP_001124323.1).
Uniprot:
Q16667
Synonyms:
CDI1;Cdk-associated protein phosphatase;CDK2-associated dual specificity phosphatase;CDK2-associated dual-specificity phosphatase;CIP2;cyclin-dependent kinase inhibitor;cyclin-dependent kinase inhibitor 3;cyclin-dependent kinase interacting protein 2;cyclin-dependent kinase interactor 1;Cyclin-dependent kinase-interacting protein 2;KAP;KAP1;kinase-associated phosphatase
Extra Details:
The protein encoded by this gene belongs to the dual specificity protein phosphatase family. It was identified as a cyclin-dependent kinase inhibitor, and has been shown to interact with, and dephosphorylate CDK2 kinase, thus prevent the activation of CDK2 kinase. This gene was reported to be deleted, mutated, or overexpressed in several kinds of cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice