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E-AB-60581

CD247 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-60581
Additional Names:
CD247,CD3-ZETA,CD3H,CD3Q,CD3Z,IMD25,T3Z,TCRZ
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human CD247 (NP_932170.1).
Uniprot:
P20963
Synonyms:
CD247 antigen, zeta subunit;CD3-ZETA;CD3H;CD3Q;CD3Z;CD3Z antigen, zeta polypeptide (TiT3 complex);CD3zeta chain;IMD25;T-cell antigen receptor complex, zeta subunit of CD3;T-cell receptor T3 zeta chain;T-cell surface glycoprotein CD3 zeta chain;T3Z;TCR zeta chain;TCRZ
Extra Details:
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Shipping Conditions:
Blue Ice