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E-AB-60532

PSMB5 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-60532
Additional Names:
LMPX,MB1,PSMB5,X
Application:
WB, IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human PSMB5
Uniprot:
P28074
Synonyms:
LMPX;macropain epsilon chain;MB1;multicatalytic endopeptidase complex epsilon chain;proteasome (prosome, macropain) subunit, beta type, 5;proteasome beta 5 subunit;proteasome catalytic subunit 3;proteasome chain 6;proteasome epsilon chain;proteasome subunit beta 5;proteasome subunit beta type-5;proteasome subunit MB1;proteasome subunit X;proteasome subunit, beta type, 5;PSX large multifunctional protease X;testicular tissue protein Li 153;X
Extra Details:
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.
Shipping Conditions:
Blue Ice