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E-AB-60498

PPP2R4 Polyclonal Antibody

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£195.30

Was £217.00

SKU:
E-AB-60498
Additional Names:
PP2A,PPP2R4,PR53,PTPA
Application:
IF
Concentration:
1 mg/ml
Purification:
Affinity Purified
Storage Conditions:
-20[o]C Avoid freeze/thaw cycles.
Supplier:
Elabscience
Host:
Rabbit
Reactivities:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant fusion protein of human PPP2R4
Uniprot:
Q15257
Synonyms:
phosphotyrosyl phosphatase activator;PP2A;PP2A phosphatase activator;PP2A, subunit B', PR53 isoform;PPP2R4;PR53;protein phosphatase 2 regulatory subunit 4;protein phosphatase 2A activator, regulatory subunit 4;protein phosphatase 2A regulatory subunit 4;protein phosphatase 2A, regulatory subunit B' (PR 53);serine/threonine-protein phosphatase 2A activator;Serine/threonine-protein phosphatase 2A regulatory subunit 4;serine/threonine-protein phosphatase 2A regulatory subunit B'
Extra Details:
Protein phosphatase 2A is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2A holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B' family. This gene encodes a specific phosphotyrosyl phosphatase activator of the dimeric form of protein phosphatase 2A. Alternative splicing results in multiple transcript variants encoding different isoforms.
Shipping Conditions:
Blue Ice